中文Imiterere mishya ya Coronavirus 501Y-V2 yo muri Afrika yepfo
Ku ya 18 Ukuboza 2020, Afurika y'Epfo yavumbuye mutant 501Y-V2 ya coronavirus nshya.Ubu mutant wo muri Afrika yepfo yakwirakwiriye mu bihugu birenga 20.Ubushakashatsi bwerekanye ko hejuru ya New Corona-virusi Mutants ishobora gutwara izindi mpinduka za Coronavirus za K417N / T, E484K na N501Y zishobora kugabanya ubushobozi bwo kutabogama kwa plasma iterwa ninkingo itangiza antibodiyite.Ariko, ugereranije na genome ya Wuh01 (numero ikurikiranye MN908947), 501Y.V2 ya genome ikurikirana ya Afrika yepfo ifite 23 nucleotide.Ifite ihinduka rya N501Y kimwe n’Ubwongereza mutant B.1.1.7, ariko iracyafite ihinduka ry’imiterere ibiri y’ingenzi E484K na K417N ya poroteyine S ishobora kugira ingaruka zikomeye ku bushobozi bwa virusi yo kwandura.
New Coronavirus ni virusi ya RNA imwe imwe, ihindagurika rya Genome ni kenshi.Kumenyekanisha intego imwe birashobora gutuma byoroshye gutahura ingero zifite virusi nkeya hamwe na virusi ihindagurika.Igipimo cyo kongera kwisuzumisha muburyo bwiza mugushakisha intego, gishobora kugera hejuru ya 10%, bishobora kongera akazi kandi bikongerera igihe cyo gusuzuma.Kugaragaza intego-nyinshi no kugenzura ibisubizo bya buri ntego birashobora kongera igipimo cyo gutahura no koroshya kwisuzumisha hakiri kare.
Igicapo 1. Igishushanyo mbonera cyuburyo bushya bwo kwandura Coronavirus
New Coronavirus Mutant B.1.1.7 yo mu Bwongereza
Ku ya 26 Ukuboza 2020, inyandiko ya mbere ya siyansi ya B.1.1.7 Strain yasohotse kumurongo.Ikigo cya kaminuza y’isuku y’i Londere mu Bwongereza n’indwara zo mu turere dushyuha, cyemeje ko umurongo wa B.1.1.7 ufite ubushobozi bwo gukwirakwira kurusha iyindi miyoboro, yari hejuru ya 56% (95% CI 50-74%).Kuberako iyi mitekerereze mishya ya mutant ifite imbaraga zo kohereza, byagaragaye ko bigoye kugenzura COVID-19.Bukeye, kaminuza ya Birmingham mu Bwongereza yashyizeho ingingo kuri MedRxiv.Ubushakashatsi bwerekanye ko umubare wa kopi ya virusi ya ORF1ab na N ku barwayi banduye imiterere ya B.1.1.7 (S-gene dropout) wiyongereye ku buryo bugaragara;iki kintu cyakurikiranwe mubaturage.Iyi ngingo yerekana ko abarwayi banduye mutant B.1.1.7 yo mu Bwongereza bafite virusi nyinshi cyane, bityo iyi mutant nayo ishobora gutera indwara nyinshi.
Igicapo 2. Urutonde rwa mutation ya genome ikubiye muri coronavirus mutant B.1.1.7 yo mubwongereza
Igicapo 3. N501Y ihinduka ryabaye mubwongereza ndetse no muri Afrika yepfoIbihinduka
Kumenyekanisha Ibikoresho bishya bya Coronavirus
Chuangkun Biotech Inc. yateguye neza ibikoresho byo gushakisha B.1.1.7 na 501Y-V2 bishya bya coronavirus.
Ibyiza byiki gicuruzwa: sensibilité yo hejuru detection icyarimwe kumenya intego 4, bikubiyemo ahantu nyamukuru hahinduwe na B.1.1.7 ihinduka ryimiterere ya mutant na 501Y.V2 ihinduka ryimiterere ya Afrika yepfo.Iki gikoresho gishobora kumenya icyarimwe kumenya N501Y, HV69-70del, E484K ya mutation na gene nshya ya coronavirus S;Ikizamini cyihuse: bifata isaha 1 gusa iminota 30 uhereye kubikusanyamakuru kugirango ubone ibisubizo.
Igicapo 4. Kumenya COVID-19 Ubwongereza butandukanye Amplification Curve
Igicapo 5. Kumenya COVID-19 Afurika yepfo Impinduka zoguhindura umurongo
Igicapo 6. Ubwoko bwishyamba bwa New coronavirus amplification curve
Ntabwo byumvikana uburyo iyi mutation ikusanya ingaruka nshya ndende z'icyorezo COVID-19 iburyo.Ariko ibi bitwibutsa ko ihinduka ryimiterere rishobora kugira ingaruka kumikorere yubudahangarwa karemano nubudahangarwa bwazanwe ninkingo.Iratwibutsa kandi ko dukeneye guhora dukurikirana coronavirus nshya igihe kirekire no kuvugurura urukingo rwa COVID-19 kugirango duhangane n’ihindagurika rya coronavirus nshya.
Igihe cyo kohereza: Werurwe-12-2021